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Membrane Stack Disc Filters Optimized for Scale Up

For Initial Filterability and Compatibility Studies

  • Used for a wide variety of applications including clarification and prefiltration, sterile filtration, and virus removal.
  • Membranes contain the same materials of construction as larger capsule and cartridge filters.  Simplify scale up and minimize requalification; no need to change materials during transitions to pilot or production scale.
  • Five membrane types offered to assure compatibility with a wide range of fluids and applications:
    • Fluorodyne® II membrane offers high flow rates and is ideal for applications where low protein binding is necessary.  Not recommended with some ethers. 
    • Supor® membrane has high flow rates and throughputs and is ideal for solutions where low protein binding is required.  Not recommended with some ketones.
    • Ultipor® membrane, the industry standard for pharmaceutical filtration, provides broad solvent and chemical compatibility, and low extractables.
    • Posidyne® membrane enhances bioburden and pyrogen removal from aqueous solutions.
    • Preflow™ media is ideal for the prefiltration of biological fluids including cell culture media, serum based products and protein solutions.

“Pall Laboratory products are designed for laboratory applications only. This product is not approved for use in medical, clinical, surgical or other patient applications. If you require further assistance in product selection for your chosen application, please contact Labcustomersupport@pall.com or call 1-800-521-1520."
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Description

For Initial Filterability and Compatibility Studies

  • Used for a wide variety of applications including clarification and prefiltration, sterile filtration, and virus removal.
  • Membranes contain the same materials of construction as larger capsule and cartridge filters.  Simplify scale up and minimize requalification; no need to change materials during transitions to pilot or production scale.
  • Five membrane types offered to assure compatibility with a wide range of fluids and applications:
    • Fluorodyne® II membrane offers high flow rates and is ideal for applications where low protein binding is necessary.  Not recommended with some ethers. 
    • Supor® membrane has high flow rates and throughputs and is ideal for solutions where low protein binding is required.  Not recommended with some ketones.
    • Ultipor® membrane, the industry standard for pharmaceutical filtration, provides broad solvent and chemical compatibility, and low extractables.
    • Posidyne® membrane enhances bioburden and pyrogen removal from aqueous solutions.
    • Preflow™ media is ideal for the prefiltration of biological fluids including cell culture media, serum based products and protein solutions.

“Pall Laboratory products are designed for laboratory applications only. This product is not approved for use in medical, clinical, surgical or other patient applications. If you require further assistance in product selection for your chosen application, please contact Labcustomersupport@pall.com or call 1-800-521-1520."

Specifications

Materials of Construction

  • Filter Media: Fluorodyne II (hydrophilic PVDF), Supor [hydrophilic polyethersulfone (PES)], Supor EKV (hydrophilic polyethersulfone), Ultipor (Nylon 6,6), and Posidyne (positivelycharged Nylon 6,6) membranes, and Preflow media (resin-bonded glass fiber)
  • Support and Drainage Layers:
       PN 61300, 61301, 61302, and 61309: Polypropylene
       PN 61303, 61304, 61306, and 61307: Polyester

Pore Size

  • 0.1, 0.2, 0.45, and 0.8/0.2 μm

Diameter

  • Filter Media: 47 mm
  • Support Layer: 37 mm

Filter Area1

  • 9.6 cm2

Recommended Integrity Test Minimum Bubble Point – Water

  • PN 61300, 61304, and 61303: 3.2 bar (320 kPa, 46 psi)
  • PN 61302: 3.5 bar (350 kPa, 51 psi)
  • PN 61309: 3.32 bar (332 kPa, 48 psi)

Bacterial Retention

  • Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision

1When used with Pall Life Sciences laboratory filter holder PN 2220; exact filter area will depend on the filter holder configuration.

Applications

  • Filtration of small volumes
  • Drug development studies
  • Validation studies
  • Determination of product compatibility

Type

Disc Filters

Use

Microfiltration

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